FruiteX-B (calcium fructoborate)

FruiteX-B, otherwise known as calcium fructoborate, is a special and highly bioavailable form of the trace mineral boron.  Boron is essential to healthy bones as it serves as a co-factor in the functions of calcium, magnesium, and vitamin D and is featured in Ortho Nutrition's™ Decalcify formula. [1], [2], [3], [4]

Decalcify features FruiteX-B, a bioavailable form of Boron, enhances calcium and magnesium metabolism, provides joint support, immune system support, and healthy aging.

Boron Helps Optimize Hormone & Mineral Balance

In a study evaluating postmenopausal women in a diet deficient in boron for 17 weeks that were then subsequently provided with dietary boron for 7 weeks afterwards, the following effects were observed; while on the boron-deficient diet, the women were found to have a decrease in calcium and magnesium. Upon fortifying their diets with boron, measures of calcium and magnesium improved, and hormones associated with healthy bone density increased.

What is FruiteX-B Exactly?

"Civilized foods," including healthy food options, are often low or devoid of adequate dietary boron requirements. This is believed to be a result of modern agriculture grown in the absence of mineral-rich soils. Therefore, even consciously healthy eating does not insure an adequate intake of dietary boron. FruiteX-B is a plant-based form of boron called calcium fructoborate. It occurs naturally in fruits, vegetables, and other foods. Additionally, unlike other forms of dietary boron, FruiteX-B is highly bioavailable.

Anti-Inflammatory Activity of FruiteX-B

A study was put together in order to evaluate the effects of short-term oral supplementation with FruiteX-B in patients with stable angina pectoris. Angina pectoris describes a condition in which there is chest pain due to lack of oxygen in the heart muscle.

The evaluation was a randomized, double-blinded, and active-controlled clinical trial which consisted of FruiteX-B supplementation for 30 and 60 days. The parameters evaluated included a marker of inflammation (high-sensitivity C-reactive protein), brain natriuretic peptide, a substance used to detect risk of heart attack and pulmonary embolism, and lipid markers (total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, and triacylglycerols).

In addition, quality of life was assessed by the Canadian Cardiovascular Society angina class and the number of angina attacks per week.

The inflammatory marker of high-sensitivity C-reactive protein in both the 30 and 60 day oral intakes of FruiteX-B found a significant decrease. This decrease was greater at 39.7% at 60 days for the FruiteX-B group.

The N-terminal prohormone of brain natriuretic peptide was significantly lowered by FruiteX-B at 52.6% at 60 days. An improvement in the quality of life for angina symptoms was also observed for subjects who received the FruiteX-B. [5]

Effect of Boron in Thyroid Metabolism

A study was carried out in order to clarify the effects of dietary boron on hormonal parameters or status, such as leptin, insulin, triiodothyronine (T3 hormone), and thyroxine (T4 hormone). [6]

Throughout an experimental period of 28 days, the mineral boron decreased leptin, insulin, and glucose levels, while increasing levels of both T3 hormone and carnitine in the blood.

The results concluded that boron supplementation in the diet enhances the metabolic activity of the test animals.

Boost Your Hormonal Function with the Mineral Boron

An evaluation was performed to determine the effects of boron on free testosterone levels in males.

In a study that evaluated men taking 10 milligrams of boron for just one week, results showed a rise in testosterone and vitamin D with a decrease in estrogen. In addition, markers of inflammation plummeted.

Such markers of inflammation were C-reactive protein (CRP), interleukin-6 (IL-6), and tumor necrosis factor-alpha (TNF-α), all of which registered significant declines.

In a study examining the relationship between FruiteX-B and vitamin D, the effects on hormones such as DHEA and Testosterone were observed. After taking 6 milligrams of boron in the form of calcium fructoborate (FruiteX-B) for 60 days, the study participantsʼ blood was tested again. The average increase in vitamin D levels was 19.6%. DHEA and testosterone were also increased 56% and 29.5% respectively.


[1]. Crit Rev Food Sci Nutr. 2001 May;41(4):225-49.

[2]. Clin Ter. 2005 Jan-Apr;156(1-2):47-56.

[3]. FASEB J. 1987 Nov;1(5):394-7.

[4]. Biol Trace Elem Res. 1991 Mar;28(3):243-55.

[5]. Nutrition. 2013 Jan;29(1):178-83.

[6]. Toxicol Ind Health. 2013 Jan 4.