Curcumin and Resveratrol as Anti-Alzheimer Agents

Within the pharmaceutical world, treatment options for Alzheimer’s disease are currently extremely limited.

Curcumin and Resveratrol work synergistically together to provide neurological protection as anti-Alzheimer agents.

Particular polyphenols, such as curcumin and resveratrol, have been shown to act as neuroprotective agents.  In other words, they have been found to provide strong anti-inflammatory support for the brain tissues. For example, they are involved in antiamyloidogenic and anti-inflammatory mechanisms. Deposition of amyloid-β and tau hyperphosphorylation are cardinal pathologic features in Alzheimer's, which lead to the formation of neuronal plaques and neurofibrillary tangles. [1]

If that sounded a little complex, it’s because it certainly is! However, in layman’s terms, this means that this supplement combo mounts an effective attack on the plaque formation and inflammatory markers (think swelling properties) associated with Alzheimer's disease, which is essentially defined as a form of brain swelling.

Curcuminoids, which are derivatives of curcumin and demethoxycurcumin, along with resveratrol, possess unique properties. One could fill up a swimming pool full of technical jargon to explain all of its anti-inflammatory mechanisms, and that is exactly why we recommend Ortho Nutrition’s™ Antioxidant Boost supplement, which contains therapeutic dosages of not only high quality Curcumin 95 and Trans-Resveratrol (99%), but also another very beneficial flavonoid in Quercetin (95%) along with a very powerful indirect antioxidant derived from broccoli sprouts known as Sulforaphane (2%).


[1]. Taiwan J Obstet Gynecol. 2012 Dec;51(4):515-25. doi: 10.1016/j.tjog.2012.09.005.